Add These Medications May Cause Sleepiness

These-Medications-May-Cause-Sleepiness.md

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+<br>For many people with a diagnosis of CBD, the journey to a diagnosis was long and confusing. It is common to have initially received a diagnosis of Parkinson’s disease because of the similarities in early symptoms. Carbidopa/levodopa: The most common medication given to people with Parkinson's that supplies dopamine to a part of the brain called the substantia nigra, which uses the medication to signal movement in the body. While the movement issues in Parkinson’s are mostly explained by damage in the substantia nigra, that area is only one of many affected areas in CBD. So, while the treatment works well for people with Parkinson’s, its benefit in CBD is unpredictable, usually modest and wears off after only a few years if there is any benefit. When taking carbidopa/levodopa for CBD, it is recommended to take a standard form of the drug, rather than the controlled- or extended-release version. People with CBD might need a high dose of the drug and should be closely monitored by the healthcare team to watch for signs of cognitive issues or dizziness.<br>
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+<br>People with CBD should be started on a low dose and gradually increase it to test tolerance and effectiveness. If there is no change in symptoms in two weeks, the maximum dose has been reached or there are any negative reactions to the medication, the medication can be tapered off and discontinued. The most common side effects can include nausea and sleepiness and issues with low blood pressure. Amantadine: This might have some benefit with gait issues, even if carbidopa/levodopa did not. Its benefit does not usually last more than a few months but can be useful for a short period. For people with CBD, the dosage should not exceed 200mg per day because of potential cognitive side effects. Entacapone (Stalevo): Taken in conjunction with carbidopa/levodopa, entacapone slows down the rate at which dopamine is broken down. This will only have an effect for people whose symptoms show a clear response to carbidopa/levodopa and have a distinct medication wear off between doses. Dopamine receptor agonists:  [Balance Bloom](http://arkhamhorror.info/index.php/User:JoannBaer3985) These drugs have no benefit in PSP beyond what carbidopa/levodopa can do. They are more likely to cause hallucinations, confusion, dizziness and nausea. Cholinesterase inhibitors: This class of medications has some benefit for cognitive loss in people with Parkinson’s or Alzheimer’s [disease](https://www.reddit.com/r/howto/search?q=disease). Muscle relaxants: Dystonic muscle spasms may potentially respond to muscle relaxants like cyclobenzaprine, baclofen or tizanidine. These medications may cause sleepiness. Levitiracetam: This medication is intended for seizures but may help with dystonic muscle spasms. Botulinum toxin (known as Botox): This is injected directly into overactive muscles or glands for blepharospasm (forced closure of the eyelids), excessive drooling, jaw clenching, involuntary bending or turning of the neck or limbs and other types of dystonia. The effect may take one to two weeks to start and should last two to three months before having to be repeated.<br>
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